Alzahrani S, Ezzat W, Elshaer RE, Abd El-Lateef AS, Mohammad HM, Elkazaz AY, Toraih E, Zaitone SA. Standarized Tribulus terrestris extract protects against rotenone-induced oxidative damage and nigral dopamine neuronal loss in mice. J Physiol Pharmacol. 2018 Dec 1;69(6):979-94. doi: 10.26402/jpp.2018.6.14.
Azam F, Amer AM, Abulifa AR, Elzwawi MM. Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: A computational investigation. Drug design, development and therapy. 2014;8:2045. doi: 10.2147/DDDT.S67778.
Ban JY, Cho SO, Choi SH, Ju HS, Kim JY, Bae K, Song KS, Seong YH. Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo. Journal of pharmacological sciences. 2008 Jan 1;106(1):68-77. doi: 10.1254/jphs.FP0071206.
Bernardo J, Ferreres F, Gil-Izquierdo Á, Valentao P, Andrade PB. Medicinal species as MTDLs: Turnera diffusa Willd. Ex Schult inhibits CNS enzymes and delays glutamate excitotoxicity in SH-SY5Y cells via oxidative damage. Food and Chemical Toxicology. 2017 Aug 1;106:466-76. doi: 10.1016/j.fct.2017.06.014.
Bernardo J, Malheiro I, Videira RA, Valentão P, Santos AC, Veiga F, Andrade PB. Trichilia catigua and Turnera diffusa extracts: In vitro inhibition of tyrosinase, antiglycation activity and effects on enzymes and pathways engaged in the neuroinflammatory process. Journal of Ethnopharmacology. 2021 May 10;271:113865. doi: 10.1016/j.jep.2021.113865.
Chan YC, Wu CS, Wu TC, Lin YH, Chang SJ. A Standardized extract of Asparagus officinalis Stem (ETAS®) ameliorates cognitive impairment, inhibits amyloid β deposition via BACE-1 and normalizes circadian rhythm signaling via MT1 and MT2. Nutrients. 2019 Jul 17;11(7):1631. doi: 10.3390/nu11071631.
Chassot JM, Longhini R, Gazarini L, Mello JC, de Oliveira RM. Preclinical evaluation of Trichilia catigua extracts on the central nervous system of mice. Journal of Ethnopharmacology. 2011 Oct 11;137(3):1143-1148. doi: 10.1016/j.jep.2011.07.032.
Chen WF, Wu L, Du ZR, Chen L, Xu AL, Chen XH, Teng JJ, Wong MS. Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways. Phytomedicine. 2017 Feb 15;25:93-9. doi: 10.1016/j.phymed.2016.12.017.
Cheng CY, Huang HC, Kao ST, Lee YC. Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK–mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats. Journal of Ethnopharmacology. 2021 Oct 5;278:114301. doi: 10.1016/j.jep.2021.114301.
Choudhary D, Bhattacharyya S, Bose S. Efficacy and safety of Ashwagandha (Withania somnifera (L.) Dunal) root extract in improving memory and cognitive functions. Journal of Dietary Supplements. 2017 Nov 2;14(6):599-612. doi: 10.1080/19390211.2017.1284970.
da Silva AL, Piato L, Ferreira JG, Martins BS, Nunes DS, Elisabetsky E. Promnesic effects of Ptychopetalum olacoides in aversive and non-aversive learning paradigms. Journal of ethnopharmacology. 2007 Feb 12;109(3):449-457. doi: 10.1016/j.jep.2006.08.022.
Deole YS, Chavan SS, Ashok BK, Ravishankar B, Thakar AB, Chandola HM. Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice. Ayu. 2011 Jul;32(3):375-9. doi: 10.4103/0974-8520.93918.
Figueiró M, Ilha J, Pochmann D, Porciúncula LO, Xavier LL, Achaval M, Nunes DS, Elisabetsky E. Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama). Phytomedicine. 2010 Oct 1;17(12):956-962. doi: 10.1016/j.phymed.2010.03.009.
Gannon JM, Brar J, Rai A, Chengappa KR. Effects of a standardized extract of Withania somnifera (Ashwagandha) on depression and anxiety symptoms in persons with schizophrenia participating in a randomized, placebo-controlled clinical trial. Ann Clin Psychiatry. 2019 May 1;31(2):123-129.
Gonzales GF, Gasco M, Lozada-Requena I. Role of maca (Lepidium meyenii) consumption on serum interleukin-6 levels and health status in populations living in the Peruvian Central Andes over 4000 m of altitude. Plant foods for human nutrition. 2013 Dec;68(4):347-51. doi: 10.1007/s11130-013-0378-5.
Gonzales-Arimborgo C, Yupanqui I, Montero E, Alarcón-Yaquetto DE, Zevallos-Concha A, Caballero L, Gasco M, Zhao J, Khan IA, Gonzales GF. Acceptability, safety, and efficacy of oral administration of extracts of black or red maca (Lepidium meyenii) in adult human subjects: A randomized, double-blind, placebo-controlled study. Pharmaceuticals. 2016 Aug 18;9(3):49. doi: 10.3390/ph9030049.
Guo SS, Gao XF, Gu YR, Wan ZX, Lu A, Qin ZH, Luo L. Preservation of cognitive function by Lepidium meyenii (maca) is associated with improvement of mitochondrial activity and upregulation of autophagy-related proteins in middle-aged mouse cortex. Evidence-based complementary and alternative medicine. 2016;2016:4394261. doi: 10.1155/2016/4394261.
Gupta M, Kaur G. Withania somnifera (L.) Dunal ameliorates neurodegeneration and cognitive impairments associated with systemic inflammation. BMC complementary and alternative medicine. 2019 Dec;19(1):1-8. doi: 10.1186/s12906-019-2635-0.
Hardiman J. Scientists make breakthrough with potential new tinnitus cure [Internet]. LADbible; 2019 [cited 2022Oct24]. Available from: https://www.ladbible.com/news/news-scientists-make-breakthrough-with-potential-new-tinnitus-cure-20190619.
Hear-it. Tinnitus causes changes in the brain [Internet]. Hear-it. 2017 [cited 2022Oct24]. Available from: https://www.hear-it.org/tinnitus-causes-changes-brain.
Kamdem JP, Olalekan EO, Hassan W, Kade IJ, Yetunde O, Boligon AA, Athayde ML, Souza DO, Rocha JB. Trichilia catigua (Catuaba) bark extract exerts neuroprotection against oxidative stress induced by different neurotoxic agents in rat hippocampal slices. Industrial Crops and Products. 2013 Oct 1;50:625-632. doi: 10.1016/j.indcrop.2013.07.033.
Kamdem JP, Waczuk EP, Kade IJ, Wagner C, Boligon AA, Athayde ML, Souza DO, Rocha JB. Catuaba (Trichilia catigua) prevents against oxidative damage induced by in vitro ischemia–reperfusion in rat hippocampal slices. Neurochemical research. 2012 Dec;37(12):2826-2835. doi: 10.1007/s11064-012-0876-0.
Kelgane SB, Salve J, Sampara P, Debnath K. Efficacy and tolerability of Ashwagandha root extract in the elderly for improvement of general well-being and sleep: a prospective, randomized, double-blind, placebo-controlled study. Cureus. 2020 Feb 23;12(2):e7085. doi: 10.7759/cureus.7083.
Khosravi MH, Saeedi M, Yousefi J, Bagherihagh A, Ahmadzadeh E. Herbal Medicine in the Management of Tinnitus. Management of Tinnitus-The Enriching Views of Treatment Options. 2018 Dec 21. doi: 10.5772/intechopen.81320.
Yasukawa K, Ko SK, Whang WK. Inhibitory Effects of the Aerial Parts of Epimedium koreanum on TPA-Induced Inflammation and Promotion in Two-Stage Carcinogenesis in Mouse Skin. Journal of Pharmacy and Nutrition Sciences. 2016 Mar 5;6(2):38-42. doi: 10.6000/1927-5951.
Kumar D, Bhat ZA, Shah MY. Anti-anxiety activity of successive extracts of Angelica archangelica Linn. on the elevated T-maze and forced swimming tests in rats. Journal of Traditional Chinese Medicine. 2012 Sep 1;32(3):423-429. doi: 10.1016/s0254-6272(13)60049-7. PMID: 23297567.
Kumar S, Madaan R, Sharma A. Pharmacological evaluation of bioactive principle of Turnera aphrodisiaca. Indian Journal of Pharmaceutical Sciences. 2008 Nov;70(6):740. doi: 10.4103/0250-474X.49095.
Laguipo ABB. Does tinnitus affect the brain? [Internet]. Medical News. 2019 [cited 2022Oct24]. Available from: https://www.news-medical.net/health/Does-Tinnitus-Affect-the-Brain.aspx.
Lei T, Li H, Fang Z, Lin J, Wang S, Xiao L, Yang F, Liu X, Zhang J, Huang Z, Liao W. Polysaccharides from Angelica sinensis alleviate neuronal cell injury caused by oxidative stress. Neural Regeneration Research. 2014 Feb 2;9(3):260-267. doi: 10.4103/1673-5374.128218.
Li LR, Sethi G, Zhang X, Liu CL, Huang Y, Liu Q, Ren BX, Tang FR. The neuroprotective effects of icariin on ageing, various neurological, neuropsychiatric disorders, and brain injury induced by radiation exposure. Aging (Albany NY). 2022 Feb 15;14(3):1562-1588. doi: 10.18632/aging.203893.
Lopez-Gonzalez MA, Esteban-Ortega F. Tinnitus dopaminergic pathway. Ear noises treatment by dopamine modulation. Medical hypotheses. 2005 Jan 1;65(2):349-352. doi: 10.1016/j.mehy.2005.02.016.
Manyam BV, Dhanasekaran M, Hare TA. Neuroprotective effects of the antiparkinson drug Mucuna pruriens. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 2004 Sep;18(9):706-712. doi: 10.1002/ptr.1514.
María DB, María VV, Lilian MN, Lucía MM, Oscar GP, Rosa ER. Neurobehavioral and toxicological effects of an aqueous extract of Turnera diffusa Willd (Turneraceae) in mice. Journal of ethnopharmacology. 2019 May 23;236:50-62. doi: 10.1016/j.jep.2019.02.036.
Marín-Tello C, Villafana-Medina H, Malpartida-Tello V, Sánchez-Marín C, Castañeda-Marín E, Vásquez-Kool J, Aliaga-Arauco J. Effect of Lepidium meyenii (maca) on spatial memory and brain oxidative damage of ovariectomised-rats exposed to mobile phone. Vitae. 2021 Apr;28(1). doi: 10.17533/udea.vitae.v28n1a342472.
Martins NO, de Brito IM, Araújo SS, Negri G, Carlini ED, Mendes FR. Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba). BMC complementary and alternative medicine. 2018 Dec;18(1):1-3. doi: 10.1186/s12906-018-2222-9.
Ng QX, Loke W, Foo NX, Tan WJ, Chan HW, Lim DY, Yeo WS. A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction. Phytotherapy Research. 2020 Mar;34(3):583-590. doi: 10.1002/ptr.6552.
Ojha R, Sahu AN, Muruganandam AV, Singh GK, Krishnamurthy S. Asparagus recemosus enhances memory and protects against amnesia in rodent models. Brain and cognition. 2010 Oct 1;74(1):1-9. doi.org/10.1016/j.bandc.2010.05.009.
Olsen MB. New Breakthrough Pill Could Cure tinnitus [Internet]. Metro; 2019 [cited 2022Oct24]. Available from: https://metro.co.uk/2019/06/18/new-breakthrough-pill-could-cure-tinnitus-10006638.
Peng Z, Bedi S, Mann V, Sundaresan A, Homma K, Gaskey G, Kowada M, Umar S, Kulkarni AD, Eltzschig HK, Doursout MF. Neuroprotective effects of Asparagus officinalis stem extract in transgenic mice overexpressing amyloid precursor protein. Journal of immunology research. 2021 May 10;2021.
Rabey JM, Vered Y, Shabtai H, Graff E, Korczyn AD. Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption. Journal of Neurology, Neurosurgery & Psychiatry. 1992 Aug 1;55(8):725-727. doi: 10.1136/jnnp.55.8.725.
Rai SN, Birla H, Singh SS, Zahra W, Patil RR, Jadhav JP, Gedda MR, Singh SP. Mucuna pruriens protects against MPTP intoxicated neuroinflammation in Parkinson’s disease through NF-κB/pAKT signaling pathways. Frontiers in Aging Neuroscience. 2017 Dec 19;9:421. doi: 10.3389/fnagi.2017.00421.
Saenghong N, Wattanathorn J, Muchimapura S, Tongun T, Piyavhatkul N, Banchonglikitkul C, Kajsongkram T. Zingiber officinale Improves Cognitive Function of the Middle-Aged Healthy Women. Evidence-Based Complementary and Alternative Medicine. 2012;2012:383062. doi: 10.1155/2012/383062.
Salazar R, Pozos ME, Cordero P, Perez J, Salinas MC, Waksman N. Determination of the antioxidant activity of plants from Northeast Mexico. Pharmaceutical Biology. 2008 Jan 1;46(3):166-170. doi: 10.1080/13880200701498952.
Saleem U, Chauhdary Z, Raza Z, Shah S, Rahman MU, Zaib P, Ahmad B. Anti-Parkinson’s Activity of Tribulus terrestris via Modulation of AChE, α-Synuclein, TNF-α, and IL-1β. ACS omega. 2020 Sep 22;5(39):25216-25227. doi: 10.1021/acsomega.0c03375.
Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019 Dec 25;11(12): e6466. doi: 10.7759/cureus.6466.
Saykally JN, Hatic H, Keeley KL, Jain SC, Ravindranath V, Citron BA. Withania somnifera extract protects model neurons from in vitro traumatic injury. Cell transplantation. 2017 Jul;26(7):1193-1201. doi: 10.1177/0963689717714320.
Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z. Icariin attenuates synaptic and cognitive deficits in an Aβ1–42-induced rat model of Alzheimer’s disease. BioMed research international. 2017 Oct;2017. doi: 10.1155/2017/7464872.
Siqueira IR, Fochesatto C, da Silva AL, Nunes DS, Battastini AM, Netto CA, Elisabetsky E. Ptychopetalum olacoides, a traditional Amazonian “nerve tonic”, possesses anticholinesterase activity. Pharmacology Biochemistry and Behavior. 2003 Jun 1;75(3):645-50. doi:10.1016/S0091-3057(03)00113-8
Siqueira IR, Fochesatto C, Torres IL, Da Silva AL, Nunes DS, Elisabetsky E, Netto CA. Antioxidant activities of Ptychopetalum olacoides (“muirapuama”) in mice brain. Phytomedicine. 2007 Nov 5;14(11):763-9. doi: 10.1016/j.phymed.2006.12.007.
Specktor B. Why do humans hear so well? you can thank the tiny 'jell-o' Violin inside your ear [Internet]. LiveScience. Purch; 2019 [cited 2022Oct24]. Available from: https://www.livescience.com/64781-jello-membrane-tunes-your-ear.html.
Sun T, Powers JR, Tang J. Evaluation of the antioxidant activity of asparagus, broccoli and their juices. Food chemistry. 2007 Jan 1;105(1):101-106. doi: 10.1016/j.foodchem.2007.03.048.
Swinbourne C. Noises in the deaf of night [Internet]. BBC News. BBC; 2008 [cited 2022Oct24]. Available from: https://www.bbc.co.uk/ouch/features/noises-in-the-deaf-of-night.shtml.
The Telegraph. Relaxed people 'heal twice as quickly' [Internet]. Telegraph Media Group; 2010 [cited 2022Oct24]. Available from: https://www.telegraph.co.uk/news/science/science-news/7814571/Relaxed-people-heal-twice-as-quickly.html.
Wattanathorn J, Jittiwat J, Tongun T, Muchimapura S, Ingkaninan K. Zingiber officinale mitigates brain damage and improves memory impairment in focal cerebral ischemic rat. Evidence-Based Complementary and Alternative Medicine. 2010;2011. doi: 10.1155/2011/429505.
Kumar D, Bhat ZA, Kumar V, Shah MY. Coumarins from Angelica archangelica Linn. and their effects on anxiety-like behavior. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2013 Jan 10;40:180-186. doi: 10.1016/j.pnpbp.2012.08.004.
Zheng H, Tai H, Zeng S. The Effect of Astragalus Membranaceus and Angelica Sinensis on Grafted Cochlea Stem Cells Apoptosis in Hearing Impaired Rats. Journal of Audiology and Speech Pathology. 1998.